Song et al retrospectively reviewed 461 cases of IPF (269 biopsy-proven) in Korea. More than a third of patients were hospitalized for respiratory deteriorations over a 2-year period. About half the deteriorations were attributed to acute exacerbations of IPF, with most of the rest attributed to infections (half the patients had BAL and/or ET aspirates as part of a separate study protocol). In news reports, this is being spun as a surprisingly low number of viral infections causing exacerbations, contradicting dogma. Half of those admitted died in-hospital; 90% of those requiring mechanical ventilation died.
Acute exacerbations of IPF portend grim outcome
Acute exacerbations of IPF portend grim…
Acute exacerbations of IPF portend grim outcome
Song et al retrospectively reviewed 461 cases of IPF (269 biopsy-proven) in Korea. More than a third of patients were hospitalized for respiratory deteriorations over a 2-year period. About half the deteriorations were attributed to acute exacerbations of IPF, with most of the rest attributed to infections (half the patients had BAL and/or ET aspirates as part of a separate study protocol). In news reports, this is being spun as a surprisingly low number of viral infections causing exacerbations, contradicting dogma. Half of those admitted died in-hospital; 90% of those requiring mechanical ventilation died.