Warfarin is the best drug for stroke prevention in atrial fibrillation. In people with a-fib for whom warfarin was unsuitable (unstable INR, unlikely adherence, etc, but excluding those with prior bleeding on warfarin), twice daily oral direct Xa inhibitor apixaban had a hazard ratio of 0.45 over aspirin for the primary outcome of stroke (absolute risk for stroke of 1.6% vs 3.7% per year), with equivalent risk for major bleeding (~1.3% per year, <0.4% for intracranial hemorrhage). The trial was funded by industry, who are also
Apixaban better than aspirin for atrial fib
Apixaban better than aspirin for atrial fib
Apixaban better than aspirin for atrial fib
Warfarin is the best drug for stroke prevention in atrial fibrillation. In people with a-fib for whom warfarin was unsuitable (unstable INR, unlikely adherence, etc, but excluding those with prior bleeding on warfarin), twice daily oral direct Xa inhibitor apixaban had a hazard ratio of 0.45 over aspirin for the primary outcome of stroke (absolute risk for stroke of 1.6% vs 3.7% per year), with equivalent risk for major bleeding (~1.3% per year, <0.4% for intracranial hemorrhage). The trial was funded by industry, who are also