After analyzing all AstraZeneca's clinical trials data on budesonide for asthma (26 placebo-controlled, n~14,000; 60 non-placebo-controlled, n~33,000), O'Byrne et al found no increased risk of pneumonia with use of budesonide by asthmatics, who contracted 1-2 detected pneumonias per 100 patient-years of treatment. AJRCCM 2011;183:589-595.