Planer et al randomized 151 smokers admitted for acute coronary syndrome to receive either bupropion sustained-release or placebo for 8 weeks. There was no difference in abstinence rates at 3, 6, or 12 months. Those who had an invasive procedure during hospitalization were 4 times more likely to quit, though. (n=151) Arch Intern Med 2011;171:1055-1060.