Ciclesonide, a new inhaled corticosteroid that seems to cause thrush less often than others, reached for equivalency with salmeterol/fluticasone in mild persistent asthma. Ciclesonide was better than placebo in controlling asthma but Advair users had a longer time to first asthma exacerbation. CHEST 2011;139: online supplement.

A Cochrane review on ciclesonide could not establish its equivalence with other ICS at higher doses with certainty, but suggested it's roughly equi-efficacious to fluticasone and other ICS.