Computer model says vanco near useless, toxic for MRSA with MIC > 1.9
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Patel et al ran 9,999 computer simulations using various vancomycin doses and MICs. When the MIC was 2.0 or greater, 2 g IV q12 hours failed to achieve target drug levels 57% of the time, with 35% predicted nephrotoxicity. But...it's also true that multiple vancomycin
Computer model says vanco near useless, toxic for MRSA with MIC > 1.9
Computer model says vanco near useless, toxic…
Computer model says vanco near useless, toxic for MRSA with MIC > 1.9
Patel et al ran 9,999 computer simulations using various vancomycin doses and MICs. When the MIC was 2.0 or greater, 2 g IV q12 hours failed to achieve target drug levels 57% of the time, with 35% predicted nephrotoxicity. But...it's also true that multiple vancomycin