Continuous antibiotic infusions for sepsis: do they save lives?
A large meta-analysis suggests benefits of prolonged beta-lactam infusions
Beta-lactam antibiotics are the most often-prescribed antimicrobials for sepsis in the ICU, with piperacillin-tazobactam, cefepime and meropenem being the most common.
Although they are usually administered in short-duration infusions, continuous infusions can maintain circulating levels of antibiotics at higher concentrations, killing microorganisms for…
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