Dexmedetomidine helpful but inadequate alone for sedation (SPICE III)
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In a new randomized trial, use of dexmedetomidine (Precedex) as the primary sedative in mechanically ventilated patients in the ICU resulted in no reduction in 90 day mortality. Dexmedetomidine resulted in a small improvement in delirium and ventilator days, but was almost never adequate to sedate patients on its own, and brought a small increase in serious adverse events The findings were reported at a major specialty society conference.
Dexmedetomidine helpful but inadequate alone for sedation (SPICE III)
Dexmedetomidine helpful but inadequate alone…
Dexmedetomidine helpful but inadequate alone for sedation (SPICE III)
In a new randomized trial, use of dexmedetomidine (Precedex) as the primary sedative in mechanically ventilated patients in the ICU resulted in no reduction in 90 day mortality. Dexmedetomidine resulted in a small improvement in delirium and ventilator days, but was almost never adequate to sedate patients on its own, and brought a small increase in serious adverse events The findings were reported at a major specialty society conference.