During lung transplant for IPF, high pulmonary artery pressure predicted graft failure
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Fang et al prospectively observed 126 patients undergoing lung transplant at 9 U.S. centers. PA pressure was obtained invasively in the OR just after transplant. Those who developed grade 3 primary graft dysfunction at 72 hours (1' endpoint) had mPAP of 38.5 mm Hg, compared to 29.6 for those who did not; the relationship persisted after multivariate analysis. Cardiopulmonary bypass attenuated the relationship. Mortality rates were higher in the high mPAP group but didn't achieve significance.
During lung transplant for IPF, high pulmonary artery pressure predicted graft failure
During lung transplant for IPF, high…
During lung transplant for IPF, high pulmonary artery pressure predicted graft failure
Fang et al prospectively observed 126 patients undergoing lung transplant at 9 U.S. centers. PA pressure was obtained invasively in the OR just after transplant. Those who developed grade 3 primary graft dysfunction at 72 hours (1' endpoint) had mPAP of 38.5 mm Hg, compared to 29.6 for those who did not; the relationship persisted after multivariate analysis. Cardiopulmonary bypass attenuated the relationship. Mortality rates were higher in the high mPAP group but didn't achieve significance.