Fidaxomicin cures C.diff infections like vancomycin; prevents more recurrences (RCT)
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Louie et al report results of a phase 3 industry-funded trial of fidaxomicin, a poorly absorbed oral macrolide that's bacteriocidal vs C. difficile. The new drug was equivalent to oral vanco in curing C.diff infections (~90%), and superior at preventing recurrences (~14% vs 24%). It did not prevent recurrences of the more lethal and increasingly prevalent NAP1/BI/027 strain of C.diff. (n=629)
Fidaxomicin cures C.diff infections like vancomycin; prevents more recurrences (RCT)
Fidaxomicin cures C.diff infections like…
Fidaxomicin cures C.diff infections like vancomycin; prevents more recurrences (RCT)
Louie et al report results of a phase 3 industry-funded trial of fidaxomicin, a poorly absorbed oral macrolide that's bacteriocidal vs C. difficile. The new drug was equivalent to oral vanco in curing C.diff infections (~90%), and superior at preventing recurrences (~14% vs 24%). It did not prevent recurrences of the more lethal and increasingly prevalent NAP1/BI/027 strain of C.diff. (n=629)
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