Immediate extubation vs. gradual ventilator weaning in comfort care

No good data exist to guide the process of withdrawal of invasive mechanical ventilation just prior to the end of life–variously known as “terminal extubation,” “compassionate withdrawal,” “extubation to comfort care,” et al.

At most centers, once the decision is made by the patient or family, an opioid infusion is initiated, all non-palliative medicati…