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In cystic fibrosis, more exacerbations worsen outcomes in adults (just like kids)

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In cystic fibrosis, more exacerbations worsen outcomes in adults (just like kids)

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Aug 30, 2011
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In cystic fibrosis, more exacerbations worsen outcomes in adults (just like kids)

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It's long been known in the pediatric cystic fibrosis population that exacerbations accelerate decline of lung function. de Boer et al show that exacerbations are just as bad or worse in adults. Following 446 adults with CF in Ontario for 3 years, those with >2 exacerbations per year had a hazard ratio of 4.05 for death or lung transplantation during the study, after controlling for confounders. Thorax 2011;66:680-685.

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In cystic fibrosis, more exacerbations worsen outcomes in adults (just like kids)

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