Ischemic stroke: Interventional treatment + alteplase = new standard of care? (MR CLEAN)
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In the early 1990s, the clot-busting drug alteplase (intravenous recombinant tissue plasminogen activator or rTPA) revolutionized stroke treatment when it was shown to significantly increase the chances of a good outcome after ischemic stroke when given in the first 4.5 hours since symptom onset. But alteplase is not a miracle drug. In a meta-analysis of 9 randomized trials, rTPA improved the chance of a good functional outcome (no significant disability at 3-6 months) by about 10% absolute (improvement from
Ischemic stroke: Interventional treatment + alteplase = new standard of care? (MR CLEAN)
Ischemic stroke: Interventional treatment …
Ischemic stroke: Interventional treatment + alteplase = new standard of care? (MR CLEAN)
In the early 1990s, the clot-busting drug alteplase (intravenous recombinant tissue plasminogen activator or rTPA) revolutionized stroke treatment when it was shown to significantly increase the chances of a good outcome after ischemic stroke when given in the first 4.5 hours since symptom onset. But alteplase is not a miracle drug. In a meta-analysis of 9 randomized trials, rTPA improved the chance of a good functional outcome (no significant disability at 3-6 months) by about 10% absolute (improvement from