Issue #5: The Latest in Critical Care, 6/19/23

Could metformin prevent long Covid? In the previously published COVID-OUT study, over 1400 patients with a new diagnosis of Covid-19 (symptoms + PCR) were randomized to receive metformin, fluvoxamine, ivermectin, placebo, or any combination thereof (six arms). No drug or combination improved the primary outcome (a composite outcome of hypoxemia, visit …