Life after sepsis protocols: What now? (You decide.)

2014 has been a rough year for advocates of sepsis protocols.

First, the long-awaited ProCESS trial did not show any benefit from use of the original early goal-directed therapy (EGDT) protocol used in the single-center 2001 trial by Rivers et al that, despite criticism, became the standard of care for the following decade. Patients cared for in the 2 n…