It would be a really strange dose/response effect if a 4% increase in the oxygenation of hemoglobin really did result in a 33% reduction in death.
There’s only so much hemoglobin. Loading it up 98% vs 94% only gets a small amount more oxygen to the tissues. If your goal is to deliver more oxygen, seems to me that you need to pay more attention to the amount of hemoglobin.
It would be a really strange dose/response effect if a 4% increase in the oxygenation of hemoglobin really did result in a 33% reduction in death.
There’s only so much hemoglobin. Loading it up 98% vs 94% only gets a small amount more oxygen to the tissues. If your goal is to deliver more oxygen, seems to me that you need to pay more attention to the amount of hemoglobin.