Eh? What'd you say? Daily azithromycin reduces COPD exacerbations, may cause hearing loss (RCT, NEJM)
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Macrolide antibiotics are increasingly recognized for their salutary anti-inflammatory effects in lung disease, potentially distinct from any antimicrobial effect. Albert et al report that among 1,142 people with severe COPD (FEV1 ~40% predicted) who were randomized to take either azithromycin 250 mg or placebo daily for one year, those taking azithromycin had fewer exacerbations, as follows:
Eh? What'd you say? Daily azithromycin reduces COPD exacerbations, may cause hearing loss (RCT, NEJM)
Eh? What'd you say? Daily azithromycin…
Eh? What'd you say? Daily azithromycin reduces COPD exacerbations, may cause hearing loss (RCT, NEJM)
Macrolide antibiotics are increasingly recognized for their salutary anti-inflammatory effects in lung disease, potentially distinct from any antimicrobial effect. Albert et al report that among 1,142 people with severe COPD (FEV1 ~40% predicted) who were randomized to take either azithromycin 250 mg or placebo daily for one year, those taking azithromycin had fewer exacerbations, as follows: