October's Seminars in Respiratory & Critical Care Medicine brings you 110 pages and 11 articles on organ failure in the intensive care unit, with articles including:

• Organ failure scoring and predictive models

• Cardiac alterations due to organ failure

• The microcirculation as a therapeutic target in shock

• Immuologic derangements in organ failure

• Acute lung failure

• Cardiogenic shock

• Gut failure

• Acute renal failure

And more. Guest editor is Jean-Louis Vincent, boss-man of the open access online journal Critical Care.

Seminars in Respiratory and Critical Care Medicine. Vol. 32, issue 5, October 2011.