Outpatient treatment for pulmonary embolism

Aujesky et al randomized 344 people in 19 European emergency departments with low-risk pulmonary embolism to either be sent home with enoxaparin and warfarin within one day, or to be treated until therapeutic on warfarin in-hospital. They were then treated for 90 days. One of 171 home-treated patients developed recurrent VTE, while none of the 168 inpatients did. Two outpatients had major bleeding; none of the inpatients did. One patient in each group died within 90 days. Lancet 2011;June 23 online.