Oxygen sensing, homeostasis, and disease (Review)

Semenza GL. Oxygen sensing, homeostasis, and disease. NEJM 2011;365:537-547.

An acronym-rich summary of decades of work by dozens of investigators eavesdropping on the secret messages cells send in response to hypoxia through HIF-1a, mTOR, VEGF and DMOG. I don't understand a word of it, frankly. (Review)