Restricting blood transfusion in patients with myocardial infarction and anemia (MINT trial)

In randomized trials totaling over 21,000 patients, restricting red blood cell transfusion until hemoglobin fell below 7 or 8 g/dL in acutely ill, hemodynamically stable patients (as compared to transfusing below 9 or 10 g/dL) resulted in a 50% reduction in blood transfused, without apparent harm.

In critically ill patients, the 1999 TRICC trial establi…