Reteplase vs alteplase for ischemic stroke

RAISE trial tests the compound against tPA in China

Alteplase (recombinant tissue plasminogen activator or r-tPA) has been widely used for many years as a reperfusion therapy for ischemic stroke. Tenecteplase (TNK–tissue‐type plasminogen activator) has recently displaced alteplase at many stroke centers thanks to its single-bolus dosing, longer half-life, greater specificity for fibrin, and possible lowe…