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Reteplase vs alteplase for ischemic stroke

RAISE trial tests the compound against tPA in China

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PulmCCM
Jun 29, 2024
∙ Paid

Alteplase (recombinant tissue plasminogen activator or r-tPA) has been widely used for many years as a reperfusion therapy for ischemic stroke. Tenecteplase (TNK–tissue‐type plasminogen activator) has recently displaced alteplase at many stroke centers thanks to its single-bolus dosing, longer half-life, greater specificity for fibrin, and possible lowe…

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