[tabby title="Introduction"] Scleroderma-Related Interstitial Lung Disease Scleroderma (SSc) is an autoimmune disease characterized by vasculopathy and fibrosis with multi organ involvement. Pulmonary complications such as interstitial lung disease (ILD) and pulmonary hypertension contribute significantly to mortality and morbidity of the disease. Up to 90% patients with scleroderma can have interstitial changes on high resolution CT scan (HRCT) and between 40-75% patients can have pulmonary function test (PFT) abnormalities. Abnormal HRCT and exam findings are often present prior to the patient’s perception of symptoms and early diagnosis requires vigilance in monitoring these patients. This review focuses on diagnosis and management of scleroderma related to interstitial lung disease (scleroderma-ILD).