Spiriva and heart attack risk: new safety kerfuffle
www.pulmccm.org
Last year, PulmCCM reported on the TIOSPIR safety trial comparing the Spiriva dry-powder HandiHaler against the Respimat mist-delivery device. TIOSPIR showed no difference in all-cause mortality or composite cardiovascular risk endpoints between either Spiriva preparation. But this week, a group of drug safety researchers report their granular analysis of TIOSPIR data shows the Respimat device (available in Europe) is associated with a three-fold increased risk of heart attack compared to the HandiHaler (the U.S. device).
Spiriva and heart attack risk: new safety kerfuffle
Spiriva and heart attack risk: new safety…
Spiriva and heart attack risk: new safety kerfuffle
Last year, PulmCCM reported on the TIOSPIR safety trial comparing the Spiriva dry-powder HandiHaler against the Respimat mist-delivery device. TIOSPIR showed no difference in all-cause mortality or composite cardiovascular risk endpoints between either Spiriva preparation. But this week, a group of drug safety researchers report their granular analysis of TIOSPIR data shows the Respimat device (available in Europe) is associated with a three-fold increased risk of heart attack compared to the HandiHaler (the U.S. device).
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