Tranexamic acid for prevention of surgical bleeding: Review

The benefits are (mostly) clear. What are the risks?

Aug 29, 2024

∙ Paid

Tranexamic acid (TXA) is a synthetic molecule derived from the amino acid lysine. TXA is a pro-coagulant that produces antifibrinolytic effects by reversibly blocking the sites where lysine binds to plasminogen, slowing down plasminogen’s clot-dissolving activity.

Epsilon-aminocaproic acid (EACA) is a related compound with antifibrinolytic activity but …

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