PulmCCM

Share this post
Xolair for inner-city kids with asthma (ICATA Trial)
www.pulmccm.org

Xolair for inner-city kids with asthma (ICATA Trial)

Mar 15, 2011
Share this post
Xolair for inner-city kids with asthma (ICATA Trial)
www.pulmccm.org

Busse et al randomized 419 inner-city kids (age 6-20) with uncontrolled, skin-test-positive, mostly severe allergic asthma and IgE < 1,300 IU/mL to 60 weeks of omalizumab or placebo. The treated group had modest improvements: ~1 fewer day of symptoms per month and a 5% absolute reduction in hospitalizations (1.5% vs 6.3%); 18% fewer of them had exacerbations (30% vs 48%), especially during fall & spring. Novartis, other pharmas and the NIH provided funding; most of the investigators reported receiving payments from Novartis. (n=419). NEJM 2011;364:1005-1015.

Share this post
Xolair for inner-city kids with asthma (ICATA Trial)
www.pulmccm.org
Comments
TopNew

No posts

Ready for more?

© 2023 PulmCCM
Privacy ∙ Terms ∙ Collection notice
Start WritingGet the app
Substack is the home for great writing