Sitemap - 2011 - PulmCCM
COPD surprise: In majority, FEV1 declines no faster than healthy people's (NEJM)
Pirfenidone for idiopathic pulmonary fibrosis (CAPACITY trials, Lancet)
Linezolid not better than vanco against MRSA pneumonia in 3rd meta-analysis (CHEST)
First report of transiently reversible brain death after induced hypothermia (Crit Care Med)
National Lung Cancer Screening Trial results (RCT, NEJM)
For empyema, tPA plus DNAse in the pleural space improved outcomes (RCT, NEJM)
Overdiagnosis of PEs on CT-angiograms seems likely (Ann Intern Med)
People with asthma perceive snake oil to work as well as albuterol (RCT, NEJM)
Cochrane review on roflumilast and cilomilast
Current Approach to the Diagnosis of Acute Nonmassive Pulmonary Embolism (Review)
Sildenafil worked in pulmonary hypertension due to CHF with preserved EF (RCT)
CT scans! Get your lung cancer-curing CT scans here -- only $99.95!
Get more sleep -- it'll improve your jump shot (Sleep)
Chantix and cardiovascular risk: meta-analysis
Diagnosis and Management of Stable COPD: A Review
Kids who sleep less get fatter? (FLAME study)
Meds often stopped after ICU stays: deaths result?
For most with OHS, ventilatory drive was oxygen-sensitive
Novel therapies for septic shock over the past 4 decades.
Surprise: Bronchoconstriction (not just inflammation) causes airway remodeling in asthma
Citing COI, IOM issues guidelines for new guidelines
ICU telemedicine shows improvements in survival, other quality outcomes (finally)
Do oral beta-blockers really exacerbate asthma?
Hypothermia looks unhelpful for out-of-hospital PEA/asystole
Ventilator-associated tracheobronchitis, or VAP?
It's official -- Someone's being too negative
Empiric antibiotics for HCAP/VAP were appropriate - yet deadly?
Cage Match! Tiotropium vs. Salmeterol in time-to-COPD exacerbation (POET-COPD)
Optimal duration of anticoagulation after VTE (Review)
Dalteparin vs. unfractionated heparin for ICU DVT prophylaxis (PROTECT Trial)
More lungs, please! Ex-vivo lung perfusion might convert bad donor lungs to good
Management of VTE Badness (Review)
More are surviving severe sepsis ... to go to LTACs
Catheter-based reperfusion in pulmonary embolism (Review)
Trouble sleeping? Don't read this, it'll only make it worse
Sildenafil appears safe, effective for long-term PAH treatment (SUPER-2)
Employers charging smokers more for medical care insurance (NYT)
Tension pneumothorax or tension bulla? (Image)
Nutrition + weights + testosterone improved function in chronic respiratory failure (RCT)
Bad livin' is protective, sort of ... mortality from 1st MI inversely related to risk factors
High-concentration oxygen caused hypoventilation in asthma exacerbation pts (RCT)
Most with ALS getting tracheotomy live longer than 1 year
Ivacaftor, a CFTR potentiator, improved lung function in certain cystic fibrosis patients (RCT)
Chronic thromboembolic pulmonary hypertension registry reveals new insights (Circulation)
Intracranial hemorrhage: A Review
Even extreme obesity doesn't reduce survival in critical illness
Bronchoscopy meds: a handy how-to guide
The reaper rarely phones ahead: Mortality prediction tools good, not great (Review)
Survival after in-ICU PEA/asystole cardiac arrest unchanged at 20 yrs
Lung cancer screening with chest CT: Pro/Con
Risk of complications after transthoracic needle biopsy: population analysis
N-acetylcysteine alone doesn't prevent contrast nephropathy after angiography
Indacaterol vs. tiotropium for once-daily COPD Rx
ECMO rising? Looks like it saved lives in H1N1 pandemic
In TB + HIV, starting antiretrovirals earlier saved lives (CAMELIA)
Triple inhaler therapy for COPD?
Reduced poverty = reduced obesity and diabetes (RCT)
Clinical decision rules for PE coagulate into meta-mishmash
Chest CT and non-PFT clinical data can detect undiagnosed COPD. But should they?
Outcomes after pulmonary metastasectomy: not too shabby
Adaptive support ventilation weaned COPD patients faster than pressure support
Talc pleurodesis safe for primary spontaneous pneumothorax, authors say
Bronchoalveolar lavage's role in diagnosis, management of interstitial lung disease (Review)
Feds at HHS release final regulations for ACOs
Asthma update: What we know we don't know (is a lot) (Review)
Pro/Con debate on mild hypothermia after out-of-hospital cardiac arrest
Too old for lung resection for NSCLC? In France, the answer is "Non!"
Death panelists unite! Advance directives restrain high-billing MDs
Coronary artery disease makes COPD symptoms worse
Think NIPPV overnight is useless for stable hypercapneic COPD? TURN IT UP, MAN!
Diagnosis of pneumothorax: Ultrasound beats chest X-ray
Asthma and genes: Polymorphism discovered that may cause steroid resistance
Septic shock: Beta-lactam levels unpredictable, need close monitoring (Review)
Severe refractory asthma: International consensus statement released
EBUS good at diagnosing TB in thoracic lymph nodes
Moviegoing U.K. teens smoke more
The price of manners: $42 million
Is your stage III NSCLC patient truly "downstaged" to N0? EUS helpful only if positive
I learned it from watching YOU, Mum!! U.K. kids smoke more when parents, siblings do
PET-CT's diagnostic accuracy plummets in region endemic for granulomatous disease (southeast U.S.)
Probiotics may prevent colds, says review
Contrast nephropathy prevented by RenalGuard's extra saline and furosemide
NSCLC: Use of biomarkers in prognosis, treatment
Montelukast improved peak flow during acute asthma exacerbations
Sarcoidosis; Interstitial lung disease; Pulmonary embolism
FACTT post-hoc: Transfusion might cure, kill or both during shock & acute lung injury...who knows?
Lifetime risk of COPD is 28% in cohort study of 13M people
New H3N2 swine flu emerges, in isolated cases only (MMWR)
Idiopathic pulmonary fibrosis: Tyrosine kinase inhibitor BIBF 1120 appeared helpful
EBUS FNA very good at finding lymph node mets from extrathoracic malignancy
COPD: Exhale airway stents didn't help (bronchoscopic lung-volume reduction EASE trial)
Pertussis vaccine wanes even faster than thought?
Effects of asthma treatment on airway remodeling
Survey says: Residents are sad, especially when they're broke
Millions of adults quit smoking since 2005 (MMWR)
Pulmonary rehab results in skeletal muscle remodeling in mild as well as severe COPD
Impedance threshold device during CPR didn't improve outcomes after out-of-hospital cardiac arrest
Lebrikizumab, an IL-13 inhibitor for asthma, improved lung function but not clinical outcomes
Toxicology in the ICU Part 1: General Overview and Approach to Treatment
People with COPD at higher risk for bad outcomes 1 year after stenting for CAD
"Changing the Course of COPD": Proceedings of the ATS (Special Issue, Review)
Sarcoidosis, Interstitial Lung Disease, Pulmonary Vascular Disease (Special Issue, Review)
Circulating fibrocytes: potential biomarker for BOS after lung transplant?
Parapneumonic effusions, empyema doubled in U.S. over past decade
In cystic fibrosis, more exacerbations worsen outcomes in adults (just like kids)
Autofluorescence vs white light bronchoscopy to diagnose lung cancer (meta-analysis, review)
Number of positive lymph nodes predicts survival in N1 non-small cell lung cancer
Tiotropium improved FEV1, but not symptoms, in severe asthma (RCT)
Subglottic drainage of secretions reduces VAP (Meta-analysis; Review)
How to reduce asthma exacerbations (Asthma Review)
Obesity associated with increased risk of severe seasonal influenza (not just H1N1)
Obstructive Sleep Apnea: An Emerging Risk Factor for Atherosclerosis (Review)
Oxygen sensing, homeostasis, and disease (Review)
It's the drugs, not the bugs, that determine survival in sepsis (but you already knew that)
Respiratory Viral Infections (Special Issue, Review)
Sleep-disordered breathing predicted future cognitive dysfunction in older women
A little longitudinal data on the enigmatic "complex sleep apnea"
Prior broad spectrum antibiotics associated with deadlier Gram-negative sepsis
Cystic fibrosis patients' nebulizer adherence under 40%
Accountability for Medical Error: Moving Beyond Blame to Advocacy (Review)
Pirfenidone's long trudge to FDA approval: InterMune launches new trial (ASCEND-3)
How many people with DVT / PE already have HIT antibodies at presentation? (And should we care?)
Inoculating pleural fluid into blood culture bottles improved yield in empyema
COPD is all in the family (or maybe just partly)
Atelectasis causes post-op fever? Doubtful.
Bronchiolitis Obliterans Syndrome: The Final Frontier for Lung Transplantation (Review)
Fundoplication for reflux associated with reduced allograft dysfunction
In COPD, there are the quick -- and the dead
Emergencies (initial management); postoperative problems (Special Issue, Review)
Nesiritide for decompensated CHF goes under the bus
Pharma to launch 5 large trials on LABA safety for asthma
Bupropion fails to improve smoking cessation post-heart attack
Self-tapering of oral steroids in severe asthma
Inactivity linked to pulmonary embolism risk
Don't exempt the mentally ill from smoking cessation efforts
People with OSA have greater impairment in endothelial function after MI
Health care 3.0 by Barry Coller
Heroes come home from Iraq, Afghanistan with constrictive bronchiolitis
After COPD exacerbation, living in the woods was a risk factor for death
Give health delivery research some respect, yo
EBUS was good at differentiating new lung cancer from recurrence
1 in 5 idiopathic pulmonary arterial hypertension patients have >2 year delay in diagnosis
Hypertonic saline for stroke with cerebral edema
Pleural effusions more common in PAH than believed?
Nasal and full-face CPAP masks generally equivalent for OSA treatment
UK investigators call entire concept of HCAP "controversial"
Tranexamic acid for intracranial hemorrhage (CRASH-2 trial)
Rapid response teams. (Review)
Long-term Course and Prognosis of Idiopathic Pulmonary Fibrosis in the New Millennium
A noninvasive test of respiratory work in COPD exacerbations that might be helpful
Exhaled hydrogen peroxide a potential biomarker for asthma?
Hyperbaric oxygen in the critically ill.
No excess risk of severe pneumonia with inhaled steroids for COPD (case/cohort study)
Glycemic Control in the ICU. Review
Single-center trials usually exaggerate effects: meta-analysis, review
Indacaterol's benefit keeps going at least through year 1
Ultrasound reduced complications of subclavian central line placement
Bone Marrow-Derived Stem Cells and Respiratory Disease. (Review)
Diseases of the pleura, and neoplasms of the lung (Special issue, review)
Omega-3 fish oils in acute lung injury had no effect (RCT)
Outpatient treatment for pulmonary embolism
Airway remodeling and its relationship to inflammation in cystic fibrosis. (Review)
Update on tuberculosis: TB in the early 21st century. (Review)
Improving survival after out-of-hospital cardiac arrest
Delaying total parenteral nutrition improved outcomes (RCT)
Patients unimpressed by flexible pressure CPAP
Wedge resection looked OK for subcentimeter NSCLC, retrospectively
Poverty did not influence mortality after ICU stays
Pro/Con debate: Measuring sputum eosinophils in severe asthma
Nicardipine beat labetalol in hypertensive emergency
Wait, 24/7 intensivist coverage is cheaper?
NYC runs smokers out of public parks, beaches
Potential metabolic consequences of statins in sepsis. (Review)
Iron deficiency common in IPAH
Pulmonary alveolar proteinosis. (Review)
Newports 1, U.S. public health 0
Mediastinal lymphadenopathy common in severe CHF?
Smokers with abnormal screening CTs keep smoking
Predictors of mortality in pulmonary arterial hypertension
Follow-up and nonpharmacological management of the idiopathic pulmonary fibrosis patient. (Review)
Progressive massive fibrosis in coal miners on the rise
Pulmonary rehabilitation, realities in clinical practice. (Review)
Tuberous sclerosis with LAM can present in adults
Recurrence risk after venous thromboembolism
Many UK immigrants have undetected latent TB; IGRA could help
Clinical decision rules for PE prospectively validated ... or were they? (Promethus study)
When after TB exposure does an interferon-gamma release assay become positive?
No negatives observed from non-MDs in MICU
V/Q, ultrasound in lieu of CT-angiography for diagnosis of PE
Defining COPD exacerbations by questionnaire
Lung vasculitis and alveolar hemorrhage. (Special Issue, Review)
Sirolimus improved chylous pleural effusions, lung function in LAM
Double your pleasure, double your fun, double your radiation
VAP prevention through GI/respiratory decontamination (meta-analysis)
Tiotropium mist (Respimat) increases mortality risk, authors say
Toward a better diagnosis of idiopathic pulmonary fibrosis. (Review)
Low vitamin D common in asthmatic children
Toxic epidermal necrolysis and Stevens-Johnson syndrome. (Review)
Texting helped smokers quit (txt2stop trial)
Cardiopulmonary arrest and cardiopulmonary monitoring. (Special Issue, Review)
Infectious complications typical after cardiac arrest
Dexamethasone for community-acquired pneumonia?
Etanercept ineffective for moderate-to-severe asthma
Patients on continuous renal replacement may need higher beta-lactam doses
Lung transplantation. (Special Issue, Review)
Minimal physical therapy didn't improve outcomes post-ICU
Update in sleep medicine 2010. (Review)
Gabapentin enacarbil for restless legs syndrome (PIVOT RLS II trial)
Parasitic infections of the lung: a guide for the respiratory physician. (Review)
Nebulized hypertonic saline reduced inflammation in CF bronchi
What the pulmonary specialist should know about the new inhalation therapies. (Review)
Weight loss effectively treated OSA in men
Augmentation common during treatment for restless legs syndrome
Trophic vs full-calorie enteric feedings for ventilated patients (RCT)
Adaptive ventilation improved complex sleep apnea in CHF patients
This is your brain on sleep apnea
Ultrasound vs. chest X-ray for dyspnea in the ER
The new perpetual squeeze on physician reimbursements
Those pesky poor people: Are they fueling the fires of burnout?
And you thought Starbucks was expensive ...
Phase III trials for aclidinium, a "me-too" antimuscarinic, in COPD (ACCLAIM I & II)
Leukotriene antagonists as good as inhalers for asthma? (RCT)
Thiazolidinediones probably increase risk for pneumonia, minimally
Data sketchy on prolonged antibiotics for bronchiectasis
Does incentive spirometry actually work?
Home testing & CPAP titration was fine for most vets with OSA
Acute lung injury & critical care update for 2010 (Review)
Docs don't discuss end-of-life care preferences with patients in clinic
Proning plus recruitment improved oxygenation in ARDS
Antibiotic dosing in multiple organ dysfunction syndrome (Review)
Rapid tests for aspergillus in BAL
Mechanical ventilation safe for pigs, and people?
CPET identified those with lung ca at high perioperative risk
The utility of cardiopulmonary exercise testing in difficult asthma
Degree of overventilation during exercise predicts bad outcomes in heart failure (Review)
Extent of lymph node dissection during lung ca resections
Beta-blockers associated with improved survival in COPD
Diagnostic value of halo and reversed-halo signs in immune-compromised hosts. (Review)
Six-minute walk test is useful in the sickest IPF patients
Diffuse parenchymal lung disease, Update for 2010 (Review)
U.S. antibiotic-fed meat crawling with resistant S. aureus
Anticholinergic inhalers associated with slightly increased risk for acute urinary retention
Grow your own new lungs -- just add some (newly discovered) stem cells!
End-stage liver disease, critical care management of (Review)
Culture may miss most PCR-confirmed, often-resistant Aspergillus
Potential new biomarker for COPD?
CPAP for OSA after stroke improved neuro outcome, reduced cardiovascular risk
Lung cancer diagnosis and treatment: summary of updated NICE guidance. (Review)
Another new TB test ("MODS") superior to smear microscopy
GOLD spirometry criteria overdiagnosed COPD
Lung cancer in COPD: enhancing surgical options and outcomes (Review)
Oral / gastric antibiotic decontamination reduced bacteremias in ICU
Nocturnal monitoring of home non-invasive ventilation (Review)
ECHO was inaccurate for pulmonary artery pressure, compared to right heart cath
Non-CPAP therapies in obstructive sleep apnea (Review)
Cystic fibrosis patients could inhale dornase alpha anytime, evidence says
What's the best long-term anticoagulation Rx after a stent for people needing warfarin?
Pseudomonas pneumonia part II, antibiotic therapy, resistance, pharmacodynamics (part 2 of 2 Review)
Comprehensive intervention improved "safety climate" in ICUs
Osteopontin a possible biomarker for IPAH?
Sleep medicine training across the spectrum (Review)
Nonwhite patients got more aggressive ICU care at end of life
Brain trust launches new CCM research database MIMIC II
Corticosteroids for ARDS from H1N1 influenza
Year in Review 2010 in pulmonary & critical care (Review)
COPD in never-smokers: BOLD unravels some of the mystery
Natural history of nonspecific pulmonary function tests
Radiographic emphysema correlated with low bone mineral density
Pramipexole for restless legs syndrome
Pro/con editorial on comparative-effectiveness research
Diesel fumes implicated as likely cause of lung cancer
Acute lung injury not improved by recombinant surfactant protein C product
Upper limit of normal for pulmonary artery pressure = 40 for endurance athletes?
Fixed-dose drug combination non-inferior to loose pills for tuberculosis
Biggest losers shed 22 pounds in Qnexa weight loss drug trial
Among Spain's healthy elderly 12 months post-ICU, the half that survived lived well
Antimicrobial "locking" of dialysis catheters prevented bloodstream infections
Transfusing freshest RBC associated with better ICU survival
Survivor after critical illness shares her story
Acute-on-chronic liver failure, concept, natural history, prognosis (Review)
Preloading with Chantix improved smoking cessation rates
Fresh frozen plasma transfusion practices: anarchy in the UK
Code status & patient expectations -- reality disconnect
Cryptogenic and secondary organizing pneumonia (Review)
Educational intervention improved asthma control in adolescents
Sleep disordered breathing plus daytime somnolence associated with early death in elderly
Vitamin D deficiency associated with mortality in critically ill
Dabigatran, a new oral thrombin inhibitor (Review)
ICU decedents' families depressed, traumatized
Delirium in the ICU, management of (Review)
Heads of beds in ICU? Use your own head, guideline critiquers say
Interferon-gamma release assays in the diagnosis of latent tuberculosis infection (Review)
New MTB/RIF test looks good for TB diagnosis
Intracerebral hemorrhage, acute management of (Review)
VAs nationwide report success of an MRSA bundle
Early vs. late percutaneous tracheotomy after cardiac surgery
Creepy ... MRSA's "MIC creep" to vancomycin portends worse outcomes
Latent tuberculosis infection in the U.S. (Review)
Predicing vancomycin failure in MRSA bacteremia
Molecular diagnosis of respiratory tract infection in COPD exacerbations (Review)
The slow death of empathy, or how we all became such jerks
Computer model says vanco near useless, toxic for MRSA with MIC > 1.9
Mucormycosis: clinical presentations and management (Review)
Outcomes after tunneled pleural catheters for malignant effusions
Post cardiac arrest syndrome: Review of therapies
Pressors and inotropes in circulatory shock (Review)
Percent positive of sampled lymph nodes predicts prognosis in N1 NSCLC
Probiotics and lung diseases (Review)
Finding PET-CT's place in mediastinal staging of NSCLC
Pseudomonas pneumonia: Epidemiology, clinical diagnosis, source (Part 1 of 2 part review)
Combining PET and volume-doubling time could improve lung nodule management
Sleep medicine, a 3,000-year history (Review)
Does CT-guided needle biopsy seed the pleura with cancer?
Status epilepticus, refractory, treatment of (Review)
Subarachnoid hemorrhage, critical care of (Review)
Elevated mesenchymal cells in BAL predicts post-lung transplant BOS
Tako-tsubo cardiomyopathy, natural history of (Review)
During lung transplant for IPF, high pulmonary artery pressure predicted graft failure
Venous thromboembolism, long term management of (Review)
Most Taiwanese chronic critically ill live ~2-6 months on the vent
Viral community-acquired pneumonia (Review)
How to lose friends and humiliate people
CPAP adherence after home sleep testing was equal to in-lab PSG
Workshop on molecular diagnostics for respiratory tract infections (Special Issue)
Combating antimicrobial resistance; Policy recommendations to save lives (Special Issue)
Candida urinary tract infections (Review)
Sleep deprivation raised BP and orthostatic tendency in elderly
Obstructive sleep apnea didn't depress cognitive function
Transtracheal oxygen therapy (Review)
Long-term oxygen therapy (Review)
Long-term complications of critical care (Review)
Why academic care isn't the best care
Quitting smoking heralds lung cancer?
TBNA usually types NSCLC correctly
Fine-toothed comb blames inhaled steroids for TB
Blood test for invasive fungal infections
Activated protein C for severe sepsis: review
Hyperoxia after cardiac arrest maybe not so bad
Hypertonic saline vs. mannitol for elevated ICP, meta-analysis
Chest tubes for transudative effusions in vented patients? Show us the data!
Weaning protocols for mechanical ventilation: review
Oral contraceptives with drospirenone increase risk of nonfatal DVT/PE (BMJ)
No racial disparities seen in Cali ICUs
Autonomy and beneficence, a historical perspective (Review)
Xolair for inner-city kids with asthma (ICATA Trial)
Critical care for patients with stroke (Review)
Budesonide didn't cause pneumonia in asthmatics
DVT of the upper extremity (Review)
Among Spain's healthy elderly 12 months post-ICU, the half that survived lived well
Hydrocortisone in multiple trauma (HYPOLYTE trial)
The effect of light on critical illness (Review)
Corticosteroids in community-acquired pneumonia
New treatments against gram-negative organisms. (Review)
Inhaled denufusol for early CF
Lymphangioleiomyomatosis. (Review)
Apixaban better than aspirin for atrial fib
Normal sleep in African-Americans and Caucasians (Review)
Chronic rhinosinusitis: oral steroid "priming" helped
Occupational asthma - Assessment, treatment, compensation (Review)
Diuretics in acute decompensated CHF
Pulmonary Sarcoidosis: Concise Clinical Review.
Treating NSCLC with tyrosine kinase / EGFR inhibitors erlotinib & gefitinib (Review)
Pregnancy and respiratory disease (Special Issue)
The upper airways and nasal passages (Special Issue)
Inspiratory muscle training liberated the hard-to-wean
The pleura and pleural diseases (Special Issue)
Cardiopulmonary exercise testing in people with heart and lung disease (Review)
Chantix worked in people with mild to moderate COPD
Point-of-care ultrasonography (Review)
Clinical Course & Prediction of Survival in Idiopathic Pulmonary Fibrosis (Review)
Is polysomnography unnecessary for diagnosis of OSA?
Sleep apnea in CHF may be dangerously underdiagnosed
Medicare wants health system change; puts $3.5B of GME's funds at risk
How industry stole the clinical trials game
Has the biomedical research-industrial complex lost its way?
Long-term survival after carcinoid resection is excellent
New non-small cell lung cancer classification system
Acute exacerbations of IPF portend grim outcome
Pulmonary artery pressure measurement by echocardiography
Exercise associated with better asthma control
Once-daily indacaterol as effective as salmeterol bid for COPD
Sirolimus was helpful for LAM, but with toxicity (RCT)
Pulmonary Complications of Lung Transplantation (Review)
Beclomethasone as rescue-therapy-only for childhood asthma
ARDS with multi-organ failure ... and more (Reviews)
Ciclesonide tests its "me too" claim vs Advair for asthma
Lung Transplant Patients with RSV: Inhaled RNA Prevents BO?
On-site path improves transbronchial needle aspiration?
Nebulized Gentamicin Helped non-CF Bronchiectasis Patients
Fidaxomicin cures C.diff infections like vancomycin; prevents more recurrences (RCT)