ICU Physiology in 1000 Words Veno-Arterial Extra-Corporeal Membrane Oxygenation (VA-ECMO) Jon-Emile S. Kenny M.D. [@heart_lung] Perhaps the most memorable patient of both my pulmonary and critical care fellowships was that of a very young woman who suffered from propofol-related infusion syndrome [PRIS]. As a consequence of PRIS, she endured multiple cardiac arrests and was placed on Veno-Arterial Extra-Corporeal Membrane Oxygenation [VA-ECMO] during cardiopulmonary resuscitation. Because of the rapid resuscitation she received from my colleagues, she survived to discharge – neuro-cognitively intact – despite spending an entire evening without cardiac activity. The details of her case may be reviewed here . The aforementioned use of VA-ECMO highlights its life-preserving capability, and underscores the importance of its hemodynamic workings.