It started with a friendly pro/con debate in the December 2011 Chest, about whether lactate clearance or mixed venous oxygen saturation is a better "goal" for early goal-directed therapy in severe sepsis and septic shock. It ended with Alan Jones reviving rumors and innuendo that have swirled around Emanuel Rivers's 2001 sepsis trial, and by extension his entire body of work.
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Should lactate clearance replace ScvO2 in…
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It started with a friendly pro/con debate in the December 2011 Chest, about whether lactate clearance or mixed venous oxygen saturation is a better "goal" for early goal-directed therapy in severe sepsis and septic shock. It ended with Alan Jones reviving rumors and innuendo that have swirled around Emanuel Rivers's 2001 sepsis trial, and by extension his entire body of work.