The Latest In Critical Care, 9/30/24 (#57)
Do thickened liquids help dysphasic patients? TNK vs tPA. New epi nasal spray.
Drinking liquids with dysphagia: the plot thickens (sorry)
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Sometimes it seems like half the ICU revolves around aspiration: accepting patients who’ve just done it, helping others not to, considering it in still others who are deteriorating, etc.
Tenecteplase (TNK) noninferior to alteplase (tPA) for ischemic stroke*
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Tenecteplase is a modified version of tissue plasminogen activator (alteplase), with a higher affinity for binding to fibrin and a longer half-life. TNK can be pushed as a single intravenous bolus, making it easier to administer than alteplase (10% of which is infused over one minute, followed by the other 90% over 60 minutes).
New nasal spray epinephrine approved by FDA
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The U.S. FDA approved an epinephrine nasal spray in August, the first nasal spray approved to treat anaphylaxis.
Physiology Flashback:
ICU Physiology in 1,000 Words: Right Ventricular Afterload (Part 1 of 2)
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ICU Physiology in 1,000 Words: