Blood transfusion targets in acute brain injury
see updated version at https://www.pulmccm.org/p/blood-transfusion-targets-in-acute
See the newest version of this post at :
Blood transfusion targets in acute brain injury: Review (Updated)
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This review was first published in October 2024; it is updated here with important new results from the SAHARA trial (English et al NEJM 2024), with a series of (rough) meta-analyses of recent data. -Ed.
TBI - traumatic brain injury - occurs after an episode of head trauma as far as I am aware! TRAIN lumped together TBI with acute intracerebral haemorrhage and subarachnoid haemorrhage so it is a study of "acute brain injury" rather than TBI! Lumping at the very least complicates the interpretation of the results and makes me wonder what Hb to aim for in a "stroke" patient or a patient with SAH! Perhaps SAHARA, the results of which will be presented in December, may help but in the meanwhile being an "aging intensivist" I advise residents that "at the very least, the Hb should be greater than the age of the patient"!