Sepsis, ID, Covid

The Latest in Critical Care: November 24, 2025

New mRNA vaccine for flu; steroids for CAP; IVC ultrasound for heart failure; transfusion in brain injury

Nov 24 •

The new goal in goal-directed sepsis therapy: Pink pinkies

ANDROMEDA-2 uses capillary refill time to drive resuscitation for sepsis

Nov 18 •

What prevents antibiotic resistance? Antibiotics

SuDDICU trial paves the way for antibiotic decontamination in ICUs

Nov 5 •

Arterial lines for shock: harms exceed benefits (EVERDAC trial)

Does this remove yet another brick in the wall of critical care dogma?

Nov 3 •

The Latest in Critical Care: October 29, 2025

PROTECT trial for VAP prophylaxis; Vitamin D to prevent AKI; Determinants of ECPR outcomes; MIND trial for surgery on ICH.

Oct 29 •

FDA set to approve "blood purification" for sepsis?

What is hemoperfusion, and can it save lives in endotoxin-related septic shock?

Oct 20 •

The Real-World Boards: Question #15

A 47-year-old man with acute heart failure and hypoxemic respiratory failure

Oct 17 •

The Latest in Critical Care: October 15, 2025

ENCOMPASS trial (telehealth post sepsis); Ambient AI scribes to reduce burnout; BRICK trial (ischemic preconditioning before cardiac cath)

Oct 15 •

The Latest in Critical Care: October 13, 2025

EVIDENCE trial post-cardiac arrest; Lateral positioning to prevent postop hypoxemia; European IV fluids guideline; antibiotic prophylaxis for variceal…

Oct 13 •

The Latest in Critical Care: October 6, 2025

Corticosteroids for critical illness; Tirofiban for stroke (ASSET IT); late tPA (HOPE trial); Does BIS monitoring help?; Adamgammadex for NMB reversal

Oct 6 •

The Latest in Critical Care: September 29, 2025

Continuous vs bolus vasopressors in surgery; Hypothermia for ischemic stroke; stem cells for ARDS; intensive BP control for ICH; more

Sep 29 •

Peripheral IVs are preferable to central lines for most patients with septic shock (Review)

CLOVERS post hoc demonstrates advantages, but don't try this without a protocol

Sep 24 •

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