Physiology

Jon-Emile S. Kenny MD [@heart_lung] In part 1, right atrial pressure [Pra] and cardiac output/venous return [CO/VR] were considered as two hemodynamic…
Jon-Emile S. Kenny MD [@heart_lung] It is axiomatic that association is not causation. Sometimes, however, this principle is lost in the fuliginous fog…
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Jon-Emile S. Kenny MD [@heart_lung] About a decade ago, a handful of terrific reviews and investigations about phenylephrine – an alpha1 agonist – were…
Jon-Emile S. Kenny MD [@heart_lung] The left ventricular ejection fraction [LVEF] is a commonly-sought cardiac measure. With the explosion of bedside…
Jon-Emile S. Kenny MD [@heart_lung] The relative simplicity of extending one’s finger onto the tissue overlaying a major artery belies the complicated…
Jon-Emile S. Kenny MD [@heart_lung] A recent review of Paul Wood’s consummate approach to pulmonary hypertension is well-worth a read [1]. In it, the…
Jon-Emile S. Kenny MD [@heart_lung] When we model the circulation at the bedside, we resort to generalizations. While these mechanistic heuristics don’t…
Jon-Emile S. Kenny MD [@heart_lung] Pulmonary Elastic Ergotrauma There are hidden hemodynamics in respiratory mechanics, as previously discussed. Recall…
Jon-Emile S. Kenny MD [@heart_lung] About a year ago, I explored blood pressure – underscoring mean arterial pressure [MAP] as a determinant, but not…
Jon-Emile S. Kenny MD [@heart_lung] Recently, Josh Farkas and Scott Weingart gave a series of engrossing posts and podcasts on asthma. I especially…
Jon-Emile S. Kenny MD [@heart_lung] Commonly, we are sold that acute pulmonary thromboembolism [PE] burns the right ventricular [RV] candle at both…
Jon-Emile S. Kenny MD [@heart_lung] What if I told you that in acute pulmonary thromboembolism [PE] that the initiation of intravenous norepinephrine…