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Hemorrhage and Hematology

Good To Know: April 24, 2025
Don't get negative about these negative trials, now
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PulmCCM
2025 Guideline on Acute Coronary Syndromes and Myocardial Infarctions
Formal guidance provided on transfusion targets, revascularization, meds and more
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PulmCCM
2
Guidelines on Red Cell Transfusion (Review)
Recommendations are conservative, but most clinicians are still liberal
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PulmCCM
3
Should thrombolytics be given >4.5 hours after stroke onset?
Improved outcomes despite intracranial hemorrhages in a new meta-analysis
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PulmCCM
2
Transfusion in acute MI: what's the right hemoglobin target?
New meta-analysis with three smaller trials adds heft to MINT
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PulmCCM
3
Blood transfusion targets in acute brain injury: Review (Updated)
Are brain injuries an exception to the "less is more" heuristic in transfusion during critical illness?
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PulmCCM
4
More data on Impella complications emerge
Six months later, DanGer-Shock post hocs add detail on AKI and bleeding
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PulmCCM
Blood transfusion targets in acute brain injury
see updated version at https://www.pulmccm.org/p/blood-transfusion-targets-in-acute
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PulmCCM
2
Albumin as resuscitation fluid for septic shock: Review
ABC-SEPSIS trial adds to aging body of evidence
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PulmCCM
7
Tranexamic acid for GI bleeds: Review
Going retro can be a gas, but not in randomized trials
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PulmCCM
2
Tranexamic acid for prevention of surgical bleeding: Review
The benefits are (mostly) clear. What are the risks?
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PulmCCM
Tranexamic acid no help during hepatic resection
Patients had same transfusion rate + more complications with TXA
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PulmCCM
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